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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK2
All Species:
12.12
Human Site:
T459
Identified Species:
29.63
UniProt:
Q8IWQ3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWQ3
NP_003948.2
736
81633
T459
P
K
E
S
P
A
G
T
P
N
P
T
P
P
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850919
676
75195
T399
P
K
E
S
P
A
G
T
P
N
P
T
P
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z98
735
81715
T460
P
K
E
S
P
A
G
T
P
N
P
T
P
P
S
Rat
Rattus norvegicus
Q8VHF0
797
88733
G501
S
S
N
A
A
S
G
G
M
T
R
R
N
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA88
798
88848
V479
R
R
H
T
L
A
E
V
T
T
H
F
Y
Q
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Q768
P
R
M
A
L
A
N
Q
Q
P
S
V
P
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
N575
N
G
S
P
M
M
N
N
S
S
P
G
M
P
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S737
A
G
G
T
A
A
T
S
S
S
S
S
S
S
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
H240
G
I
Y
T
L
P
S
H
L
S
S
E
A
R
D
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
S632
P
K
S
P
S
R
Y
S
L
S
R
R
A
I
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
89.8
N.A.
97.9
25.4
N.A.
N.A.
27.4
N.A.
25.1
N.A.
50.9
N.A.
23.1
N.A.
Protein Similarity:
100
N.A.
N.A.
90.3
N.A.
98.7
43.2
N.A.
N.A.
43.9
N.A.
37.9
N.A.
63.5
N.A.
37.3
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
6.6
N.A.
N.A.
6.6
N.A.
26.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
20
N.A.
N.A.
20
N.A.
40
N.A.
20
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
33.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
20
20
60
0
0
0
0
0
0
20
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
30
0
0
0
10
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
20
10
0
0
0
40
10
0
0
0
10
0
0
20
% G
% His:
0
0
10
0
0
0
0
10
0
0
10
0
0
0
20
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
30
0
0
0
20
0
0
0
0
0
0
% L
% Met:
0
0
10
0
10
10
0
0
10
0
0
0
10
0
0
% M
% Asn:
10
0
10
0
0
0
20
10
0
30
0
0
10
0
0
% N
% Pro:
50
0
0
20
30
10
0
0
30
10
40
0
40
50
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
0
0
10
0
% Q
% Arg:
10
20
0
0
0
10
0
0
0
0
20
20
0
10
0
% R
% Ser:
10
10
20
30
10
10
10
20
20
40
30
10
10
10
30
% S
% Thr:
0
0
0
30
0
0
10
30
10
20
0
30
0
10
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _